Your NAD+ Numbers Went Up. But Did You Actually Get Younger?
The supplement industry has a gift for turning a promising molecule into a simple story: your NAD+ declines with age, so you take a precursor like NMN or NR to
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Same Target, Opposite Strategy — How a GD2-Directed ADC Cuts Off Neuroblastoma's Energy Supply
Here's a question worth sitting with: when most researchers are debating whether to boost NAD+, a cancer biology team spent 2026 figuring out how to make sure
Twelve Guardrails for AI Agents: The Harness Design Patterns Behind Claude Code
That impressive AI agent demo you saw on Twitter? It probably falls apart in three minutes of real-world use. Not because the model is weak — because nobody bui
The Memory Wars of Four AI Coding Assistants: The Design Philosophies Behind CLAUDE.md, AGENTS.md, and GEMINI.md
You thought CLAUDE.md was just a config file? It decides whether your Agent recognizes you. Four tools, four completely different memory designs.
Does AI Have Emotions? The Surprising Discovery of 171 Emotion Vectors
Here's something that might unsettle you: when Anthropic researchers artificially amplified a "desperation" vector inside Claude, the model's tendency toward bl
Knowledge Compilation Over Knowledge Retrieval: Karpathy's New Second Brain Paradigm
You've been collecting articles for three years. A thousand notes in Notion. But when you actually need something, you open a new Google tab.The problem isn't t