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Cancer Cells May Fear Rust More Than Apoptosis

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A 2025 review places mitochondria at the center of ferroptosis: four firewalls decide whether cancer cells die by lipid peroxidation. This is a mechanism map, not proof of human benefit.

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Homemade TMAO in β-cells: a local brake on NF-κB senescence

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Draft only. Wang et al. (Nat Commun 2026) show pancreatic β-cells produce TMAO via FMO3 to stabilize IκBα, limit NF-κB-driven senescence/inflammation, and preserve GSIS—distinct from circulating TMAO risk narratives.

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Beyond Weight Loss — How Semaglutide Quiets the Immune Storm in Your Brain

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GLP-1 receptor agonist semaglutide reverses high-fat diet-induced hippocampal microglia activation via the IGFBPL-1/PI3K/AKT pathway in mice. This article explores the molecular bridge from gut hormones to brain protection — and the gap between animal data and clinical reality.