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Lab Grimoire
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v1.3

Dot Blot

Changes (4)
  • Toolbar regrouped into detection, edit mode (Select / Add / Delete with shortcut hints) and history, with grid, crop, templates and spot meanings on a second row
  • A four-step workflow bar and a status line above the image explain the current mode; rotation, zoom, contrast and history now sit in a collapsible panel so the image appears higher on the page
  • Clicking a results row highlights it, and the signal column shows a bar relative to the strongest spot; keyboard shortcuts V, A, D, C, Esc and Cmd/Ctrl+Z are supported
  • Undo after dragging an ROI now returns it to where it was, and the page no longer scrolls sideways on narrow screens
v1.0

Western Blot

Changes (4)
  • New Western blot densitometry tool — frame all lanes with one box, and lanes are counted, split at the faintest columns and centred on their signal
  • One horizontal drag marks the band in every lane at once; the second row defaults to the loading control, and Snap bands corrects smiling gels lane by lane
  • Lane-baseline, border-median or no background correction; loading-control normalisation and fold change vs a chosen control group
  • Bar chart builds itself from lane groups with mean ± SD or SEM, individual points and Holm-adjusted Welch tests vs control, exportable as PNG/SVG alongside CSV
v1.4

Flow Cytometry

Changes (4)
  • Analysis mode keeps the plot in front. Choose a gate tool and drag on the plot to make the first gate; axis details and export open when you need them, while session restore stays visible.
  • Add up to four plots and assign a sample by dragging it from the file list or choosing it above the plot. A gate drawn on that plot belongs to that sample.
  • Selecting a sample no longer hides it. Show and hide are separate controls.
  • Skipping compensation is labeled on that sample, so an uncompensated file does not look unchanged. Files uploaded together stay in the order you selected.
Post

When the Heart's Drain Pipes Clock Out: Aging Lymphatics and Cardiac Inflammation

Details

A Nature Cardiovascular Research mouse and cell study finds that aging thins cardiac lymphatics and tightens their junctions, making immune cells and waste harder to clear. Nuclear IL-33 and falling VEGFC are the mechanistic clues. Restoring VEGFC rebuilt vessel density and cut macrophages, but did not fix diastolic function. This is not proof of a human therapy.