Your Longevity Genes Are Starving — The NAD+ Crisis Behind Sirtuin Shutdown
Seven longevity genes evolved over a billion years sit idle without NAD+. Imai and Guarente's classic npj review on why sirtuins need fuel to extend lifespan.
Open →Your Cells Are Running Out of Time — Scientists Just Found the Pause Button
By 50 you have half the NAD+ you had at 20. Imai's NAD World 3.0 framework in npj Aging cracks the cellular supply chain behind mammalian aging and the pause button.
Open →Your DNA Gets Attacked Thousands of Times Daily — Why Haven't You Turned Into Cancer?
Your DNA takes over 10,000 oxidative hits per day. NLRP10 is the fire alarm that keeps that damage from cascading into cancer. Researchers just mapped exactly how it detects double-strand breaks — and what happens when it goes silent.
Open →Slice a Flatworm Into Pieces. Its RNA Memory Still Survives.
No brain, no neurons, yet planarian flatworms encode molecular memories in RNA that survive being cut in half and regrown, rewriting where memory can actually live.
Open →Your Fat Cells Are Aging — And a Probiotic Might Be Able to Turn Back the Clock
Here's something most people never think about: your fat cells have an age.Not in the way you track your birthday, but biologically — there's a version of your
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