Long-form analysis at the intersection of AI and life sciences — all spells, sorted by time.
Telomeres are usually cast as the cell's countdown timer that hits zero and you age. But two studies show they manage far more than time: shorten them, and immune cells' mitochondria misfire, inflammation ignites, and cognition takes a causally-linked hit. Telomeres, it turns out, move both inflammation and brainpower.
You took NMN for three months and still look the same in the mirror. Why? Three landmark studies piece together how NAD⁺ collapses with age: how cells fake hypoxia, who eats your supplements, and whether topping NAD⁺ back up can truly rejuvenate old cells.
We've heard plenty of mouse stories about NAD⁺ falling with age. Three studies finally move it onto real humans: a tube of blood, a brain scan, and a randomized double-blind trial each confirm NAD⁺ truly declines in us, while honestly flagging that the clinical payoff is still unsettled.
The pitch writes itself: as you age, cellular NAD+ levels decline, mitochondria lose their fuel, and muscles begin to waste away. Take NMN or NR daily, restore
In 2026, NMN entered its first clinical trial for autoimmune disease and appeared in Nature Medicine. Combined with new evidence on T cell senescence reversal and exercise-driven SIRT1 activation, three studies map NAD+ as an immune calibrator.
A few years ago, a startup was charging people tens of thousands of dollars to infuse them with plasma from young donors. The FDA eventually issued a statement: