Research Journal · Academic Notes

Grimoire

Long-form analysis at the intersection of AI and life sciences — all spells, sorted by time.

📖 Literature Mar 16, 2026

Your Longevity Genes Are Starving — The NAD+ Crisis Behind Sirtuin Shutdown

Seven longevity genes evolved over a billion years sit idle without NAD+. Imai and Guarente's classic npj review on why sirtuins need fuel to extend lifespan.

#science#biomedical#NAD+#Sirtuins

📖 Literature Mar 12, 2026

Every Time You Run, Your Brain Secretly Grows New Neurons

177 peer-reviewed studies confirm aerobic exercise triggers neurogenesis, reduces amyloid plaques, and measurably slows Alzheimer's progression. It is the most evidence-backed brain intervention that no doctor is currently required to prescribe.

#science#biomedical#neuroscience#exercise

Grimoire

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Your Longevity Genes Are Starving — The NAD+ Crisis Behind Sirtuin Shutdown

Every Time You Run, Your Brain Secretly Grows New Neurons