Long-form analysis at the intersection of AI and life sciences — all spells, sorted by time.
By 40, your mitochondria run on half the NAD+ they had at 20. How NAD+ decline and the SIRT3 switch dim your cellular power plants, and what the science says about fighting the brownout.
# Rewinding the Biological Clock: Telomerase Reactivation and the New Science of Epigenetic Age 
NMN and NR do raise blood NAD+. But the science shows the benefits are real, limited, and work nothing like supplement ads claim. Here is what actually holds up.
Think about a phone you've had for a few years. You've swapped the screen. You cleared the storage. But the battery? It just doesn't hold a charge anymore. By n
Picture a city. Every building needs electricity. When the power grid starts failing, you don't just lose the lights — hospitals shut down, water treatment stop
Seven longevity genes evolved over a billion years sit idle without NAD+. Imai and Guarente's classic npj review on why sirtuins need fuel to extend lifespan.