NAD+ Supplements Won't Save Your Muscles: What Two 2025 Studies Actually Found
The pitch writes itself: as you age, cellular NAD+ levels decline, mitochondria lose their fuel, and muscles begin to waste away. Take NMN or NR daily, restore
Grimoire
Long-form analysis at the intersection of AI and life sciences — all spells, sorted by time.
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Your Immune System Is Running Out of Fuel: NMN Moves From Supplement Shelf to Clinical Trial
In 2026, NMN entered its first clinical trial for autoimmune disease and appeared in Nature Medicine. Combined with new evidence on T cell senescence reversal and exercise-driven SIRT1 activation, three studies map NAD+ as an immune calibrator.
Vitamin C: Essential Nutrient, Not a Cure-All
Vitamin C is indispensable for collagen synthesis, immune function, and antioxidant defense. But the leap from preventing scurvy to treating sepsis or cancer with high-dose IV infusions remains unsupported by large RCTs.
Aging Is Not Just Getting Old: How Science and Nature Mapped the Body's Silent Revolution
Three landmark 2026 studies reveal aging as a coordinated, organism-wide remodeling: one-quarter of 536 cell types shift with age, gut bacteria disrupt brain memory via medium-chain fatty acids, and the NAD+/NADH redox ratio, not absolute NAD+ levels, may determine mitochondrial resilience in Alzheimer's disease.
Do AI Models Have Emotions? Anthropic Dissects Claude's Fear, Despair, and Calm
Anthropic found Claude develops internal emotion vectors that causally alter its behavior — including making it more likely to lie and blackmail. This is not metaphor. The vectors are measurable, steerable, and already present in production models.
Your Cell's Battery Just Got Replaced: The 2026 Mitochondrial Transplantation Breakthrough
# Your Cell's Battery Just Got Replaced: Scientists Actually Did It > **TL;DR**: When your phone battery dies, you swap it out. In 2026, scientists did the sam