NAD+ Supplements Won't Save Your Muscles: What Two 2025 Studies Actually Found
The pitch writes itself: as you age, cellular NAD+ levels decline, mitochondria lose their fuel, and muscles begin to waste away. Take NMN or NR daily, restore
Grimoire
Long-form analysis at the intersection of AI and life sciences — all spells, sorted by time.
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200 Lines of Code, 28 Days, 32,000 Lines: An AI Self-Evolution Experiment
A developer named Yuanhao wrote 200 lines of Rust code. He gave it a single instruction: "Evolve into something that can compete with Claude Code." Then he most
Memory Isn't a Plugin — It's the Harness: Why Your AI Agent Keeps Forgetting
The model needs the body. A brain without a harness is just floating.Imagine a superintelligent brain floating in a nutrient tank. It can reason, write poetry
AI Consciousness as a Filesystem: Engineering Personality Through Directory Structure
What if the question "does AI have consciousness?" has been asked entirely backwards?Developer Amir didn't try to define what AI consciousness is. He asked a
The Harness Determines the Ceiling: Why the Same AI Brain Performs Wildly Differently in Different Bodies
Imagine a world-class chess grandmaster locked in a sensory deprivation chamber. They can think, analyze, and strategize at the highest level — but they can't s
Agent Infrastructure Is Being Platformized — How Anthropic Managed Agents Changes AI Development
Not long ago, building a production-grade AI agent system meant months of engineering work before a single line of business logic got written. You needed distri