Long-form analysis at the intersection of AI and life sciences — all spells, sorted by time.
Jakob Nielsen argues that AI is triggering the first major UI paradigm shift in 60 years: users are becoming supervisors instead of operators, delegating intent rather than issuing commands. This rewrites the definition of usability and introduces three crises: the articulation barrier, the credibility trap, and the cognitive wheelchair.
A single AI Agent is reliable. But your cognitive bandwidth caps at 5 parallel threads. Skill Graphs 2.0 introduces a three-layer architecture — atoms (deterministic), molecules (fixed sequence), compounds (strategic autonomy) — turning 5 compound-level tasks into 500 work units. This article breaks down the framework, practical principles, and known limitations.
Anthropic, the UK AI Safety Institute, and the Alan Turing Institute have demonstrated that inserting just 250 carefully crafted documents into training data can plant a permanent backdoor in LLMs ranging from 600M to 13B parameters. Bigger models and more data do not dilute the poison.
The early days of mainstream AI use had a particular competitive currency: prompt quality. Who could write the most precise, most creative, most effective instr
Here's a tax you probably pay every day without noticing.You need to translate an article. You open your AI tool and start typing the prompt you've written a do
You've probably noticed it. An hour into a complex conversation, your AI assistant starts making mistakes it shouldn't. Repeating itself. Forgetting decisions i