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var(--border);background:var(--accent-bg-soft);flex-shrink:0}.pf-drawer-title[data-astro-cid-xmm7rnjh]{font-family:var(--font-display);font-size:1rem;font-weight:700;color:var(--accent-light)}.pf-drawer-close[data-astro-cid-xmm7rnjh]{width:2rem;height:2rem;display:inline-flex;align-items:center;justify-content:center;font-size:1.5rem;line-height:1;color:var(--text-muted);background:transparent;border:1px solid transparent;border-radius:var(--radius-sm);cursor:pointer;transition:all .2s ease}.pf-drawer-close[data-astro-cid-xmm7rnjh]:hover{color:var(--accent-light);background:var(--surface-tint)}.pf-drawer-body[data-astro-cid-xmm7rnjh]{flex:1;overflow:auto;padding:1.25rem;display:flex;align-items:flex-start;justify-content:center}.pf-drawer-body[data-astro-cid-xmm7rnjh] .protocol-figure[data-astro-cid-xmm7rnjh]{margin:0;width:100%}.pf-drawer-body[data-astro-cid-xmm7rnjh] .protocol-figure-img[data-astro-cid-xmm7rnjh]{width:100%;height:auto;display:block}.pf-drawer--landscape[data-astro-cid-xmm7rnjh] .pf-drawer-body[data-astro-cid-xmm7rnjh]{align-items:center}.pf-drawer--landscape[data-astro-cid-xmm7rnjh] .pf-drawer-body[data-astro-cid-xmm7rnjh] .protocol-figure[data-astro-cid-xmm7rnjh]{max-width:1100px}@media(prefers-reduced-motion:reduce){.pf-drawer[data-astro-cid-xmm7rnjh]{transition:none}}.progress-bar-container[data-astro-cid-xmm7rnjh]{position:sticky;top:0;z-index:50;padding:.75em 1em;margin-bottom:1.5em;border-radius:var(--radius-md);border:1px solid var(--border);background:var(--bg-card-solid);box-shadow:var(--card-shadow-rest);display:flex;align-items:center;gap:1em}@supports (backdrop-filter: blur(1px)){.progress-bar-container[data-astro-cid-xmm7rnjh]{backdrop-filter:blur(16px);-webkit-backdrop-filter:blur(16px)}}.progress-bar-text[data-astro-cid-xmm7rnjh]{font-size:.85em;font-weight:600;color:var(--text-primary);white-space:nowrap}.progress-bar-track[data-astro-cid-xmm7rnjh]{appearance:none;-webkit-appearance:none;flex:1;height:8px;border-radius:4px;background:var(--bg-secondary);overflow:hidden;border:0}.progress-bar-track[data-astro-cid-xmm7rnjh]::-webkit-progress-bar{background:var(--bg-secondary);border-radius:4px}.progress-bar-track[data-astro-cid-xmm7rnjh]::-webkit-progress-value{border-radius:4px;background:linear-gradient(90deg,var(--accent) 0%,var(--bio-green) 100%)}.progress-bar-track[data-astro-cid-xmm7rnjh]::-moz-progress-bar{border-radius:4px;background:linear-gradient(90deg,var(--accent) 0%,var(--bio-green) 100%)}.progress-remaining[data-astro-cid-xmm7rnjh]{font-size:.8em;color:var(--text-muted);white-space:nowrap}.version-mismatch-banner[data-astro-cid-xmm7rnjh]{padding:.75em 1em;border-radius:var(--radius-sm);border:1px solid var(--warning-border);background:var(--warning-bg);color:var(--warning-color);font-size:.85em;margin-bottom:1em;display:flex;align-items:center;gap:.5em}.related-protocols[data-astro-cid-xmm7rnjh]{margin-top:3em;padding-top:2em;border-top:1px solid var(--border)}.related-protocols[data-astro-cid-xmm7rnjh] h2[data-astro-cid-xmm7rnjh]{font-size:1.3em;margin-bottom:1em}.related-card[data-astro-cid-xmm7rnjh]{display:inline-block;padding:1em 1.25em;border-radius:var(--radius-md);border:1px solid var(--border);background:var(--bg-card);color:var(--text-primary);text-decoration:none;transition:all .2s;margin-right:1em;margin-bottom:.75em}.related-card[data-astro-cid-xmm7rnjh]:hover{border-color:var(--accent-border-hover);transform:translateY(-2px);color:var(--text-primary)}.anim-pipette[data-astro-cid-xmm7rnjh]{animation:pipetteDrop 2s ease-in-out infinite}.anim-centrifuge[data-astro-cid-xmm7rnjh]{animation:centrifugeSpin 1.5s linear infinite}.anim-heat[data-astro-cid-xmm7rnjh]{animation:heatPulse 2s ease-in-out infinite}.anim-shake[data-astro-cid-xmm7rnjh]{animation:shakeMotion .5s ease-in-out infinite}.anim-incubate[data-astro-cid-xmm7rnjh]{animation:incubatePulse 3s ease-in-out infinite}.anim-wash[data-astro-cid-xmm7rnjh]{animation:washWave 2s ease-in-out infinite}@keyframes pipetteDrop{0%,to{transform:translateY(0)}30%{transform:translateY(-4px)}50%{transform:translateY(2px)}}@keyframes centrifugeSpin{0%{transform:rotate(0)}to{transform:rotate(360deg)}}@keyframes heatPulse{0%,to{opacity:1;transform:scale(1)}50%{opacity:.7;transform:scale(1.15)}}@keyframes shakeMotion{0%,to{transform:translate(0)}25%{transform:translate(-3px)}75%{transform:translate(3px)}}@keyframes incubatePulse{0%,to{opacity:.6}50%{opacity:1}}@keyframes washWave{0%,to{transform:translate(0)}25%{transform:translate(3px)}75%{transform:translate(-3px)}}@media(prefers-reduced-motion:reduce){.anim-pipette[data-astro-cid-xmm7rnjh],.anim-centrifuge[data-astro-cid-xmm7rnjh],.anim-heat[data-astro-cid-xmm7rnjh],.anim-shake[data-astro-cid-xmm7rnjh],.anim-incubate[data-astro-cid-xmm7rnjh],.anim-wash[data-astro-cid-xmm7rnjh]{animation:none!important}}@media(max-width:640px){.protocol-grid[data-astro-cid-xmm7rnjh]{grid-template-columns:1fr}.protocol-hero[data-astro-cid-xmm7rnjh]{padding:1.25em}.protocol-hero[data-astro-cid-xmm7rnjh] h1[data-astro-cid-xmm7rnjh]{font-size:1.5em}.panel-grid[data-astro-cid-xmm7rnjh]{grid-template-columns:1fr}.protocol-timeline[data-astro-cid-xmm7rnjh]{padding-left:2em}.step-node[data-astro-cid-xmm7rnjh]{left:-2em;width:18px;height:18px}.step-header[data-astro-cid-xmm7rnjh]{padding:.75em 1em}.step-check-btn[data-astro-cid-xmm7rnjh]{min-height:44px}.progress-bar-container[data-astro-cid-xmm7rnjh]{flex-wrap:wrap}.protocol-meta[data-astro-cid-xmm7rnjh]{gap:.4em}.category-filters[data-astro-cid-xmm7rnjh]{gap:.35em}}.tools-hero[data-astro-cid-xmm7rnjh],.protocol-hero[data-astro-cid-xmm7rnjh],.materials-panel[data-astro-cid-xmm7rnjh],.progress-bar-container[data-astro-cid-xmm7rnjh],.step-card[data-astro-cid-xmm7rnjh],.related-card[data-astro-cid-xmm7rnjh],.protocol-card[data-astro-cid-xmm7rnjh],.protocol-empty-state[data-astro-cid-xmm7rnjh]{border-radius:1.45rem;border:1px solid var(--input-border);background:radial-gradient(circle at top left,var(--surface-glow),transparent 28%),linear-gradient(180deg,var(--surface-overlay),var(--bg-card-raised));box-shadow:var(--box-shadow)}.tools-hero[data-astro-cid-xmm7rnjh],.protocol-hero[data-astro-cid-xmm7rnjh],.materials-panel[data-astro-cid-xmm7rnjh],.progress-bar-container[data-astro-cid-xmm7rnjh],.protocol-empty-state[data-astro-cid-xmm7rnjh]{padding:clamp(1.15rem,3vw,1.7rem)}.tools-hero[data-astro-cid-xmm7rnjh]{margin-bottom:1.5rem}.tools-hero-badge[data-astro-cid-xmm7rnjh]{display:inline-flex;align-items:center;justify-content:center;min-height:40px;margin-bottom:1.15rem;padding:.5rem .95rem;border-radius:999px;border:1px solid var(--accent-border-hover);background:var(--surface-glow);font-family:var(--font-mono);font-size:.72rem;letter-spacing:.14em;text-transform:uppercase;color:var(--bio-cyan)}.tools-hero[data-astro-cid-xmm7rnjh] h1[data-astro-cid-xmm7rnjh],.protocol-hero[data-astro-cid-xmm7rnjh] h1[data-astro-cid-xmm7rnjh],.materials-panel[data-astro-cid-xmm7rnjh] h2[data-astro-cid-xmm7rnjh],.related-protocols[data-astro-cid-xmm7rnjh] h2[data-astro-cid-xmm7rnjh]{font-family:var(--font-display)}.category-filters[data-astro-cid-xmm7rnjh]{display:flex;flex-wrap:wrap;gap:.6rem;margin:0 0 1.4rem}.category-pill[data-astro-cid-xmm7rnjh]{min-height:42px;padding:.62rem 1rem;border-radius:999px;border:1px solid var(--input-border);background:var(--header-bg);color:var(--text-secondary)}.category-pill[data-astro-cid-xmm7rnjh]:hover,.category-pill[data-astro-cid-xmm7rnjh].active{border-color:var(--accent-border-hover);background:var(--surface-glow);color:var(--text-primary)}.protocol-grid[data-astro-cid-xmm7rnjh]{gap:1rem}.protocol-card[data-astro-cid-xmm7rnjh]{position:relative;overflow:hidden;display:grid;gap:.8rem;padding:1.2rem;transition:transform .22s ease,border-color .22s ease,background .22s ease}.protocol-card[data-astro-cid-xmm7rnjh][hidden]{display:none!important}.protocol-card[data-astro-cid-xmm7rnjh]:hover,.related-card[data-astro-cid-xmm7rnjh]:hover{transform:translateY(-3px);border-color:var(--accent-border-hover);background:linear-gradient(180deg,var(--bg-card-hover),var(--bg-card-raised))}.protocol-card[data-astro-cid-xmm7rnjh]:before{content:"";position:absolute;inset:6px;border:1px solid var(--accent-bg-soft);border-radius:calc(var(--radius-lg) - 4px);pointer-events:none;z-index:0}.protocol-card[data-astro-cid-xmm7rnjh] .card-svg-bg[data-astro-cid-xmm7rnjh]{width:60%;height:60%}.protocol-card[data-astro-cid-xmm7rnjh]:hover .card-svg-bg[data-astro-cid-xmm7rnjh]{opacity:.08;transform:scale(1.1) rotate(-5deg);color:var(--accent-light)}.protocol-card-category[data-astro-cid-xmm7rnjh],.protocol-card[data-astro-cid-xmm7rnjh] h3[data-astro-cid-xmm7rnjh],.protocol-card[data-astro-cid-xmm7rnjh] p[data-astro-cid-xmm7rnjh],.protocol-card-meta[data-astro-cid-xmm7rnjh]{position:relative;z-index:1}.protocol-card-category[data-astro-cid-xmm7rnjh],.protocol-card-duration[data-astro-cid-xmm7rnjh],.protocol-card-steps[data-astro-cid-xmm7rnjh],.protocol-meta[data-astro-cid-xmm7rnjh] span[data-astro-cid-xmm7rnjh],.progress-bar-text[data-astro-cid-xmm7rnjh]{font-family:var(--font-mono);font-size:.72rem;letter-spacing:.1em;text-transform:uppercase}.protocol-card[data-astro-cid-xmm7rnjh] p[data-astro-cid-xmm7rnjh],.protocol-hero[data-astro-cid-xmm7rnjh] p[data-astro-cid-xmm7rnjh],.materials-panel[data-astro-cid-xmm7rnjh] li[data-astro-cid-xmm7rnjh],.related-card[data-astro-cid-xmm7rnjh] p[data-astro-cid-xmm7rnjh],.protocol-empty-state[data-astro-cid-xmm7rnjh],.version-mismatch-banner[data-astro-cid-xmm7rnjh]{color:var(--text-secondary)}.protocol-card-difficulty[data-astro-cid-xmm7rnjh]{border-radius:999px;padding:.38rem .75rem;border:1px solid var(--input-border);background:var(--surface-tint)}.step-card[data-astro-cid-xmm7rnjh]{overflow:hidden;border:1px solid var(--input-border);background:linear-gradient(180deg,var(--surface-overlay),var(--bg-card-raised))}.step-number[data-astro-cid-xmm7rnjh]{background:var(--surface-glow);border-right:1px solid var(--surface-glow);color:var(--bio-cyan)}.step-tip[data-astro-cid-xmm7rnjh],.step-warning[data-astro-cid-xmm7rnjh],.version-mismatch-banner[data-astro-cid-xmm7rnjh]{border-radius:1rem}.progress-bar-container[data-astro-cid-xmm7rnjh]{top:0;background:var(--bg-card-solid);box-shadow:var(--card-shadow-rest)}.progress-bar-track[data-astro-cid-xmm7rnjh]{background:var(--surface-tint-hover)}.related-card[data-astro-cid-xmm7rnjh]{padding:1rem 1.15rem}.protocol-empty-state[data-astro-cid-xmm7rnjh]{display:grid;place-items:center;text-align:center;min-height:180px}.protocol-actions[data-astro-cid-xmm7rnjh]{display:flex;flex-wrap:wrap;gap:.5rem;margin-top:1rem}.protocol-action-btn[data-astro-cid-xmm7rnjh]{font:inherit;font-size:.85rem;padding:.4rem .85rem;border-radius:999px;border:1px solid var(--border);background:var(--bg-secondary);color:var(--text-secondary);cursor:pointer;transition:border-color .15s ease,color .15s ease}.protocol-action-btn[data-astro-cid-xmm7rnjh]:hover,.protocol-action-btn[data-astro-cid-xmm7rnjh]:focus-visible{border-color:var(--accent-border-soft);color:var(--accent-light)}.protocol-print-sheet[data-astro-cid-xmm7rnjh]{display:none}@media 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0}.print-checklist[data-astro-cid-xmm7rnjh]{list-style:none;padding-left:0;margin:0}.print-checklist[data-astro-cid-xmm7rnjh] li[data-astro-cid-xmm7rnjh],.print-procedure[data-astro-cid-xmm7rnjh]>li[data-astro-cid-xmm7rnjh]{break-inside:avoid;margin:.35rem 0}.print-procedure[data-astro-cid-xmm7rnjh]{padding-left:0;list-style:none}.print-step-action[data-astro-cid-xmm7rnjh]{font-weight:600}.print-step-body[data-astro-cid-xmm7rnjh]{margin:.15rem 0 0 1.4rem;font-size:10pt}body{background:#fff!important;color:#000!important;font-size:11pt}a[data-astro-cid-xmm7rnjh][href]:after{content:""}}.search-filter-container[data-astro-cid-xmm7rnjh]{display:flex;flex-direction:column;gap:1.5rem;margin:1.5rem 0 2rem}@media(min-width:768px){.search-filter-container[data-astro-cid-xmm7rnjh]{flex-direction:row;align-items:center;justify-content:space-between}}.search-box[data-astro-cid-xmm7rnjh]{position:relative;width:100%;max-width:380px}.search-box[data-astro-cid-xmm7rnjh] input[data-astro-cid-xmm7rnjh]{width:100%;padding:.55rem 1rem .55rem 2.5rem;border-radius:var(--radius-sm);border:1px solid var(--border);background:var(--bg-card);backdrop-filter:blur(10px);-webkit-backdrop-filter:blur(10px);color:var(--text-primary);font:inherit;font-size:.9rem;outline:none;transition:border-color .3s ease,box-shadow .3s ease}.search-box[data-astro-cid-xmm7rnjh] input[data-astro-cid-xmm7rnjh]::placeholder{color:var(--text-muted)}.search-box[data-astro-cid-xmm7rnjh] input[data-astro-cid-xmm7rnjh]:focus{border-color:var(--accent);box-shadow:0 0 12px var(--accent-glow)}.search-icon[data-astro-cid-xmm7rnjh]{position:absolute;left:.9rem;top:50%;transform:translateY(-50%);font-size:.9rem;opacity:.6;pointer-events:none}.nslist__aside[data-astro-cid-xmm7rnjh] .section-hero{margin-bottom:0}.nslist__aside[data-astro-cid-xmm7rnjh] .search-filter-container[data-astro-cid-xmm7rnjh]{flex-direction:column;align-items:stretch;gap:1rem;margin:0}.nslist__aside[data-astro-cid-xmm7rnjh] .search-box[data-astro-cid-xmm7rnjh]{max-width:none}.nslist__aside[data-astro-cid-xmm7rnjh] .search-box[data-astro-cid-xmm7rnjh] input[data-astro-cid-xmm7rnjh]{background:transparent;border-radius:var(--radius-sm)}.nslist__aside[data-astro-cid-xmm7rnjh] .search-box[data-astro-cid-xmm7rnjh] input[data-astro-cid-xmm7rnjh]:focus{box-shadow:none;border-color:var(--accent)}.nslist__aside[data-astro-cid-xmm7rnjh] .category-filters[data-astro-cid-xmm7rnjh]{display:flex;flex-wrap:wrap;gap:.5em}.nslist__aside[data-astro-cid-xmm7rnjh] .category-pill[data-astro-cid-xmm7rnjh]{background:transparent;border:1px solid var(--border)}.nslist__aside[data-astro-cid-xmm7rnjh] .category-pill[data-astro-cid-xmm7rnjh]:hover,.nslist__aside[data-astro-cid-xmm7rnjh] .category-pill[data-astro-cid-xmm7rnjh].active{background:transparent;border-color:var(--accent);color:var(--accent-light)}.nslist__scroll[data-astro-cid-xmm7rnjh] .protocol-browse[data-astro-cid-xmm7rnjh]{margin-top:0}.nslist__scroll[data-astro-cid-xmm7rnjh] .protocol-grid[data-astro-cid-xmm7rnjh]{grid-template-columns:repeat(2,minmax(0,1fr))}